Hidradenitis Suppurativa and Crohn’s Disease: Two Cases with Different Disease Courses

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Abrar F. Khojah
Yousif A. Qari https://orcid.org/0000-0002-8049-8106

Keywords

Adalimumab, Crohn’s disease, Hydradenitis suppurativa, Infliximab

Abstract

Hidradenitis suppurativa is a rare chronic / recurrent, infl ammatory and suppurative disease that affects apocrine gland-bearing areas of the skin, including the axillae, inframammary fold, inguinal and anogenital regions. Few reports have described the co-occurrence of Hidradenitis suppurativa and Crohn’s disease and the challenge in managing patients with both conditions. We describe two cases in which HS developed during the course of Crohn’s disease in one patient, while it preceded the onset of Crohn’s disease in the other case. Both patients showed poor response to biological therapy although one case initially responded well to induction therapy with infliximab.

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